EGCG and HIV Treatment
HIV/AIDS: Chemical in green tea may help treat HIV
December 2009
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According to research from Baylor College of Medicine and Texas Children’s Hospital, a
chemical naturally found in green tea, epigallocatechin gallate (EGCG), might help prevent HIV
infection. Green tea is already popular due to its antioxidant properties.
From the Houston Business Journal:
In previous studies, Dr. Christina Nance, assistant professor of pediatrics at BCM, and
Dr. William Shearer, professor of pediatrics at BCM, had demonstrated that
epigallocatechin gallate — EGCG — found in green tea, inhibited infection in a specific
HIV-1 strain.
The latest discovery shows EGCG can inhibit infection in multiple HIV-1 strains.
“This is paramount from a global aspect,” Nance said. “Most initial studies with HIV-1
in the Americas are based on subtype B.” However, she added, most of the world is
infected with other strains.
“EGCG may represent a potential low-cost inhibitor of global HIV-1 infection that could
be used at least as adjunctive anti-HIV therapy,” said Nance and Shearer in their report.
Previous drugs developed to block the entry of HIV-1 into cells proved ineffective
because the virus mutated. Nance hopes that EGCG, derived from a natural product,
will be less likely to generate such mutations.
Other Relevant:
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Green Tea (EGCG) Aids in fighting against HIV. Researchers have found EGCG in green tea can reduce HIV binding to human CD4 cells by as much as 40%.
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Inhibition of HIV-1 infectivity across subtypes by the green tea catechin, epigallocatechin gallate (EGCG), without altered immune function
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Green Tea Compound Being Developed as Potential HIV-1 Therapy
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Green Tea for HIV Treatment?
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Green Tea Blocks HIV in Test Tubes. An antioxidant in green tea may block HIV, the virus that causes AIDS, from attaching to an important molecule on immune system cells.
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